10 Common Medications That Can Cause Loss of Balance

These drugs can cause orthostatic hypotension—a sudden drop in blood pressure when standing—leading to:

• Dizziness
• Blackouts
• Falls

5. Diuretics (“Water pills”)

Examples:
Lasix, Hydrochlorothiazide

They reduce fluid in the body, which can:

• Lower blood volume
• Drop blood pressure
• Cause weakness and dizziness

6. Antihistamines (Allergy & motion-sickness drugs)

Examples:
Benadryl, Meclizine, Promethazine

They often cause:

• Drowsiness
• Confusion
• Poor coordination

Especially dangerous at night.

7. Opioid Painkillers

Examples:
Morphine, Oxycodone, Hydrocodone

These drugs depress the nervous system and can cause:

• Sedation
• Dizziness
• Loss of balance

They greatly increase fall risk.

8. Sleep Medications

Examples:
Ambien, Lunesta

These drugs can cause next-day grogginess and confusion, making walking unsafe.

9. Anti-seizure & nerve-pain drugs